17.10.15

DEXTROMETHORPHAN

antitussive, NMDA antagonist 

Brands/Synonyms : Adult Dry Cough, AeroTuss 12, Alka-Seltzer Plus Coughand Cold Formula, 

Alka-Seltzer Plus Flu Formula, Vicks 44 Cough Relief, Vicks Nature Fusion Cough and Chest Congestion, Triaminic Long-Acting Cough, Vicks Formula 44, etc.


Indications

Administration : 

Dosage (Dog) 2 mg/kg PO q 12h

Duration As clinically necessary (2 weeks in 1 study)

Expected Effects 

Significant reduction in pruritus, based on owner observations (placebo-controlled, double-blinded).

Therapeutics

Soundalike Alert : Dextroamphetamine


Available Formulations : 

Tab  Many. in over-the-counter human cough preparations


Oral solution   Many. in over-the-counter human cough preparations

Precautions

Contraindications :  Hypersensitivity to the drug, Purposeful cough (e.g., pneumonia)


Pearls

Anecdotal use for cough suppression in dogs and cats: 1-2 mg/kg PO q 8-12h
Historically considered only for its antitussive properties; now recognized to have central nervous system effects that may produce analgesia and/or behavior modification (and the potential for human abuse of the drug)



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